The Duke SMILE Studies: Can Exercising Replace Antidepressants?
Blumenthal and colleagues conducted several randomized controlled trials in 2000 comparing the effects of aerobic exercise to antidepressant medication. These were called the SMILE (Standard Medical Intervention & Long-term Exercise) studies. For the record, depression is a common disorder that is associated with compromised quality of life, increased health care costs, and greater risk for [...]